Lebanonian Cedar Alignment COG1325
166 positions
7 sequences
12 branches
Lebanonian Cedar 5 branch
3 sequences
Supplied by 29 positions
of alignment
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Information about tree branches Right arrow
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                   +-44-+-45-*AF2318
| | | +-33-+-55-*APE1451
| | | +-29-+-58-*MJ0213
| | | +-37-+-9--*PH1876
| | | +-5--*PAB1135
| +-44-+-54-*MTH689
| +-56-*VNG1287C

Look at the tree. One of its branches is extracted.
It is supported by 29 positions - that's written on the scheme.
Let's consider some positions. E. g, in the position number 107 phenylalanine in sequences of the marked groups is placed opposite lysine in all other sequences (out of branch). It's an ideal case: alignment is divided into two clear groups, this division is the same with those, given by the branch.

More widespread is the case when positions consists of three or more amino acids. But on the one side of the branch (usually - inside the branch) one amino acid is placed. Such are positions number 5 (leucine opposite isoleucine, valine and methyonine), 30 (glutamic acid opposite arginine, glycine and serine), 51 (threonine opposite alanine, phenylalanine and serine), 55 (phenylalanine opposite leucine, histidine and tyrosine), 111 (phenylalanine opposite isoleucine, leucine and valine), 123 (valine opposite isoleucine, leucine and proline), 137 (lysine opposite glutamine, glutamic acid and valine), 139 (phenyalalnine opposite tyrosine and gap) and 155 (valine opposite alanine, isoleucine and leucine).
It's worth mentioning, that positions 30, 51, 111 and 137 are better that other ones - because two groups are presented by principially different acids (in position 5, for comparison, all aminos - isoleucine, leucine, methyonine and valine - are rather similar in their physico-chemical properties).

Positions of the third group (6, 7, 26, 38 - 42, 44, 60, 63, 68, 84, 91, 96, 106, 143, 154 and 158) are rather non-homogeneous. Though two classes of aminoacids (those which are present in the branch and these which present out of it) don't intersect, they are rather wide for clear distinquishing the branch. That's why it's no use paying attention on them.

Right arrow Alignment
Red-coloured are conserved positions
Green-coloured are positions, supplying this branch in sequences of this branch
Blue-coloured are positions, supplying this branch in other sequences of alignment
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1   5    10   15   20   25   30   35   40   45   50   55   60   65   70   75   80   85   90   95   100 
|   |    |    |    |    |    |    |    |    |    |    |    |    |    |    |    |    |    |    |    |   
PH1876 MGKRLQAHNVKIRTFIHATEDPEKVLEALETLFPEDISPKDVDFEVIE--TEGYFGNPILVVDAEIRHSRNVRKFLENLRNSLSEEDR--KYLLEHAEEK
PAB1135 MAGKLQAHNIRIRTFIHATEDPEKVLEALETLFPEEISPKDVEFEVIE--TEGYFGNPILVVDAEIKHSRNIRKFLENLRGLLSKEDR--KYLWEHAEEK
AF2318 MKGKIEW--VRVSAVVHSTEDREKVGEAISTLFPFEF-----EIAVSK--AKGHYGNPMEYLEVELTKSSEIKKFWKNLLELLG-EQA--EEILSTLEDR
MTH689 MRDMIHN--ISYRLMVYGTEDEEKVIEALRNVIPGAT------PERES--AEGYHGNPITVLRGRLDRRRALREFMEKFTEVFR-------GRMDELEDR
VNG1287C -MSEVPFHYIDLRVFCYDTEADSRVADALGHFLPEDV-----EIERTD--SEGHLGDRIGVLSTRVERADDMRHVLDQLRDGAD---I--EQIRDQLDER
APE1451 MSRMMGVSWLEARVSVHATEDREKVVRALSNILPLSGG----KIEVVEDVFEGHYGNQIRVITVRIKDGRTASKVLEDILSKLPSHDR--RYLLETLEER
MJ0213 ---MLNS--IKLSAIVHATEDEDKVLEAIEFFIPENVDEEKIDLDVVE--TQGYFGNPIKIINVNVE-GKEAKKIFKHIIDLIKSDDKNINKLKKDLHLR
|   |    |    |    |    |    |    |    |    |    |    |    |    |    |    |    |    |    |    |    |   
1   5    10   15   20   25   30   35   40   45   50   55   60   65   70   75   80   85   90   95   100 
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101 105  110  115  120  125  130  135  140  145  150  155  160  1166 
|   |    |    |    |    |    |    |    |    |    |    |    |    ||   
PH1876 VDETGTFYIRFDKQKAYLGEIKVSEGQDVIHVRIKVKAF-P-MRKEAV---VNAVKKWLEGEE---
PAB1135 VDETGTFYIRFDKQKAYLGEVKVSEGEDVIHVRIKVKAF-P-MKKEAV---VKAVREWLEGED---
AF2318 IDEQNVLHIRIDKQKAYLGEVSLTSGGDPIAVKLRLVTY-P-SKREKV---IEFARELCTIS----
MTH689 FDENGNLFLRLDKQKALEGVWEPVRHGDAIHLKIKVEAY-P-AKREVA---VENIRKILE------
VNG1287C VDDNCSLFVHLDKQAAYLGDAQL---GDGISLRAKVEAY-P-AKKDAA---VENARDALAD-----
APE1451 VDKNGVLYIRVSKQDAYLGEARIYEGDDVIRIAVGFQG----GRRKAVSFYRELLKRLLEGKADRG
MJ0213 VEDN-KFYVRFDKQKAYLGECRVVDGDDIIRAVFNFKIFTPKNKEEKV---KEIVANELGF-----
|   |    |    |    |    |    |    |    |    |    |    |    |    ||   
101 105  110  115  120  125  130  135  140  145  150  155  160  1166 
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