ETS family


General information Species distribution Numeration assumed Sequence conservation 3D conservation Contacts with DNA

Species distribution for ETS proteins

   According to Pfam database there have been found 487 ETS genes to date, most of which turned out to belong to different species of animal kingdom. One ETS protein was found in avian leukemia virus E26 and no such proteins were found in plants or Fungi.
   Among animals, ETS genes were found in Annelida (7 proteins), Mollusca (4), Porifera (3), Ctenophora (1), Nematoda (24), Cnidaria (3), Chordata (388), Arthropoda (47), Platyhelmintes (1) and Echinodermata (8).

   The following table shows the number of ETS genes present in genomes of most intensively studied species.

The number of ETS genes found in genomes of most intensively studied species
SpeciesThe number of ETS genes
Homo sapiens66
Mus musculus86
Drosophila melanogaster17
Caernorhabditis elegans12
Xenopus laevis30


   The following table shows the number of well studied ETS proteins and their distribution among species.

List of well studied ETS proteins and their distribution among species
SpeciesThe number of ETS proteinsProteins
Homo sapiens24SPI (B and C), ETV (1-7), ELF (1-5), SPI1 (a.k.a. PU1), ELK (1 and 4, a.k.a. SAP2 and SAP1), ETS (1 and 2), GABP alpha, ERF, SPDEF, FLI1, ERG
Mus musculus23SPI (B and C), ETV (1-6), ELF (1, 2, 4, 5), SPI1 (a.k.a. PU1), ELK (1 ,3 ,4),ETS (1 and 2), GABP alpha, ERF, SPDEF, FLI1, ERG
Rattus norveqicus3ETS1, SPI1, SPIB
Bos taurus1ELF5
Sus scrofa1SPI1
Gallus gallus4ETS1 (A and B), ETS2, ERG
Drosophila melanogaster9ETS (3, 4 and 6), ELG, POK, E74E (A and B), PNT (1 and 2)
Xenopus laevis5FLI1, ETS1 (A and B), ETS1 (A and B)
Danio rerio1PEA3
Avian leukemia virus E261MYBE_AVILE

See also PROSITE documentation
© A.Grishin, A.Alexeevski, A.Karyagina, S.Spirin

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